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When mice drank normal water again, the gene shut off and the mice turned white.
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Given free access, mutant mice drank twice as much alcohol as normal mice.
Green tea at concentration of 3% (w/v) was given orally to treated mice as sole source of drinking water from the end of the 4th week to the end of 10th week post-infection; untreated mice were allowed to drink normal water.
D2L KO mice drank significantly more ethanol than WT in both sexes.
KO mice drank more sugar water than WT in females but not in males.
Combined injured mice drank more water than sham-treated mice.
(i) mice drank glucose; and (ii) drank glucose plus doxycycline in water.
However, TRPV1 knockout mice drank significantly more from drinking tubes treated with eugenol than wildtype mice.
Likewise, mice were randomly allocated in the two treatment groups: (i) mice drank 1% glucose; and (ii) drank 1% glucose plus 2 mg/ml doxycycline in water.
When tumors reached a homogeneous size they were randomly allocated into two treatment groups: (i) mice drank glucose; and (ii) drank glucose plus doxycycline in water.
NPY knockout mice drink more alcohol than wild-type mice, implicating a link between NPY deficiency and high alcohol intake.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com