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We found that changes in BM progenitor numbers in tumor-free mice dosed with GCSF mice paralleled those observed in tumor-bearing mice.
No ricin was detected in the feces of mice dosed intravenously.
Antibody neutralization assays have been applied previously to mice dosed with BoNT [25].
No difference in onset or disease severity was observed between mice dosed with PBS and treated with the different combinations of mAbs, except those mice dosed with PBS + anti-TGF-β mAb recovered sooner from the acute disease (Figure 5B).
After 24 hpi, we could not detect the ricin in feces in mice dosed with 200 µg/mouse or less.
The resultant protection of dystrophin-deficient fibres by continued expression of utrophin resulted in a reduction in the level of regeneration taking place in skeletal muscle in mdx mice dosed with SMT C1100.
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The doses of lovastatin used in our study were lower when compared with the human maximum dose (80 mg per day): the 0.44 mg kg��1 and 8.3 mg kg−1 of mice doses correspond to daily human doses of 2.15 and 40.14 mg assuming an average human body weight of 60 kg.
HDM sensitised control mice were dosed with control mouse IgG (10 mg/kg mAb 101.4) accordingly.
Preventative studies involving bacteria pre-dosing: five mice were dosed once daily by oral gavage with MRx0004 (5 × 108 CFU/mouse) and another five mice were dosed with vehicle (YCFA; 400 µL/mouse) from D-14 to D17.
Therapeutic studies without bacteria pre-dosing: five mice were dosed once daily with MRx0004 (5 × 108 CFU/mouse) from D7 to D17.
Researchers from Sahmyook University in Seoul, South Korea, fed lab mice doses of dried milk powder from cows milked both during the day and night mixed with water.
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