However, differently from humans and mice, dog studies are hindered due to a more restricted repertoire of commercially available monoclonal antibodies (mAb) against cytokines [ 10].
Our observation that expression of mRNA for the transcription factor gene Irx5 is inversely related to Kv4.2 (that is, it is significantly higher in ENDO than EPI) is consistent with observations in mice, dog [ 5] and rats [ 34].
GDF8 is a major regulator of pre- and postnatal growth and specifically muscle development in many vertebrate species including mice, dog, sheep, cattle, horse and human [ 7, 10, 11, 16, 18].
Deficiency in hypocretin neurotransmission results in the sleep disorder narcolepsy in mice, dogs, and humans.
It seems to prefer people, but it also does well on mice, dogs, guinea pigs, birds and cats.
He helped lead the company to the suvorexant molecule, and ran the first tests on rats, mice, dogs, and rhesus monkeys.
We evaluated the RV-RabG variants in several animal models (mice, dogs, and pigs) and demonstrated that a single dose elicited high titers of rabies virus-neutralizing antibodies and protected animals from live rabies virus challenge (mice and dogs).
Since Kenyon's pioneering work began, other studies have shown that mutations in the daf-2 genes of mice, dogs, and other mammals also extend life span.
Vessel viability was assessed using 0.3 μmol l−1 norepinephrine (in hamsters), or 10 μmol l−1 phenylephrine (in mice, dogs, pigs and humans), or 60 mmol l−1 KCl (humans).
The anti-aging effects of the compound, resveratrol, mimic those of a calorie-restricted diet, which has been shown to give mice, dogs, and worms longer, healthier lives.
Since then, scientists have cloned mice, dogs, cats, pigs, horses and cattle, although mutliple attempts to clone monkeys have failed, as have attempts to produce cloned human embryos.
