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The humoral response of infected mice does not appear capable of killing surviving cysticerci.
Global deletion of Syndecan2 in mice does not affect viability and fertility of mice.
HCT leading to sustained mixed chimaerism in well-established diabetic mice does not achieve similar results39.
In addition, transplantation of monolayer cells into nude mice does not result in tumor formation nor affects the tumorigenicity of sphere cells, when grafted together with monolayer cells.
A mouse will tell you in two weeks.Yet replacing monkeys with mice does not cut the number of animals used.
Oral ribitol administration from pregnancy to adult of the P448L mice does not affect pregnancy, embryo development, body weight, and overall behavior of the mutant mice.
Extended Data Fig. 8 Expression of mVEGF-C in the meninges of J20 mice does not ameliorate lymphatic drainage or brain amyloid pathology.
Sommerstein et al. have elegantly demonstrated that LASV exposure or immunization in mice does not induce LASV NAbs due to the LASV GPC's glycan shield28.
"If I was a betting person, my guess is that it probably won't work in humans," Dr. Buse added, explaining that all too often in science what works in mice does not work in people.
What works in mice does not necessarily work in people.
Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com