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Not surprisingly, the running mice displayed much greater endurance than the loungers.
Immunohistochemical evaluation of pancreata from Hq mutant mice displayed much smaller islets compared to wild-type mice (WT).
As expected, dKO mice displayed much higher levels of miR-1 and miR-206 in the blood compared with wild-type controls (Fig. 8A and B).
In contrast, the brains of nSSL-BMS-treated mice displayed much lower levels of the proinflammatory cytokines and chemokines IFN- γ, TNF, CCL-2, and CXCL-9.
We found that on selective inhibition of 12/15-LO 12/15-LO mice displayed much milder EAE symptoms despite their competent peripheral T-cell response.
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With a three-generation F
Such values were never detected in the other 3 strains examined, and may readily explain why the Mbnl1 ΔE3/ΔE3/mice3 ΔE2 mice display much more pronounced myotonia than the Mbnl1 ΔE3/ΔE3 animals.
On both trials R6/1 mice displayed a much lower number of USVs than their WT littermates [F 1,29) = 10.38, p<0.01; Fig. 4-B], and this effect was significant only in males, R6/1 mice emitting nearly no vocalizations at all [sex×genotype: F 1,29) = 4.25, p<0.05; post-hoc: p<0.05; Fig. 4-B].
As expected, the BALB/c mice displayed a much higher viral RNA load than the 129SvEv mice.
However, during the test periods, CSE-treated mice showed strong preferences for the novel object, while vehicle-treated mice displayed a much lesser preference for it.
In contrast, Cln1/5 dko mice displayed a much more pronounced accumulation of autofluorescent material (Fig. 2A), and this was already seen in 1-month-old Cln1/5 dko mice (data not shown).
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