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These mice displayed approximately a ∼40% reduction in complex V (ATP5a1) and III (Uqcrc2) (Fig. 5D).
Similarly, neonatal Hq mice displayed approximately 50% smaller infarcts after hypoxia-ischemia.
Adult Hq mice displayed approximately 40% smaller infarcts in a model of focal ischemia and 44% less secondary contusion expansion after traumatic brain injury.
In consistency with 'Beige' cell development, ingWAT but not eWAT, from KO mice displayed approximately twofold increase in β-oxidation rates (Fig 4J and model summarized in supplementary Fig S7 online).
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Compared with untreated mice, mice treated with TAM, CXB, or both displayed approximately 1.5-, 1.2-, and 2.0-fold increases, respectively, in splenocyte proliferation.
In the subcutaneous colon tumour models, mice treated with 10 mg kg−1 NS-398 displapproximatelyately 50 70% of the tumour burden compared to control animals.
Mice with late onset beta cell-specific Pdx1 inactivation displayed approximately 60% of the normal number of beta cells and 10% of total pancreatic insulin content compared to wild type mice at three weeks of age.
HpyAV variant H295A displayed approximately 1% of wt activity.
and is displayed approximately 20 mins later.
In TLR2/4-/ mice, the increase in the E. coli numbers was also strongly alleviated, if compared to wt mice (P<0.001), and these mice displayed only an approximately 10-fold rise in E. coli after colitis induction (Figure 5A).
RFP immunohistochemistry on brain sections revealed that 4D mice displayed mosaic RFP expression, with approximately 30 40% of cells in the VZ being RFP+.
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