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Here, we demonstrate that DAT-KO mice display lower hippocampal theta oscillation frequencies during baseline periods of waking and rapid-eye movement sleep.
Moreover, DAT-KO mice display lower peak HTO frequencies than WT mice during periods of REM sleep where both genotypes of mice are behaviorally inactive.
These mice display lower plasma levels of IGF-1, lower oxidative stress and a metabolic profile which resembles that observed in calorie-restricted wild-type animals.
The mammary glands of Csf1 op / op mice display lower numbers of terminal end buds as well as reduced ductal branching and elongation [ 4].
Therefore, the NK cells in SHIPi treated mice display lower levels of effector functions using both receptor-specific and unspecific stimulation.
In contrast, DMH/LH-specific Nkx2-1 or Sirt1-knockdown mice (Satoh et al., 2013) and DMH-specific Prdm13-knockdown mice display lower NREM delta power compared to controls.
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Female C57 and LID mice displayed lower body, heart and liver weights compared to male counterparts.
Interestingly, ribavirin-treated mice displayed lower LVTs than that of zanamivir-treated animals, but the values were not statistically significant (P > 0.5) (Fig. 1C).
However, αCGRP knockout mice displayed lower pain sensitivity to heat stimulation faster accumulation of c-Fos compared to wild-type animals after incision and complete Freund's adjuvant injection [104].
Furthermore, lymph nodes taken from AnxA1null mice displayed lower SGPP2 gene activity.
CAG200 mice displayed lower grip strength and reduced locomotor activity, indicating that these mice may have muscle weakness and altered energy metabolism.
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