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In addition to obvious differences such as small size and short lifespan, mice differ from humans in a range of anatomical, physiological, energetic, electrophysical, and mechanical properties that include heart rate, coronary artery structure, and contraction/relaxation kinetics.
Hr(N) mice differ from other Hr mutants in that hair loss appears as the postnatal coat begins to emerge, rather than as an inability to regrow hair after the first catagen and that the mutation displays semi-dominant inheritance.
Surprisingly these mice differ from Mc1r mutant mice as they have a pain response indistinguishable from mice with a functional Mc1r.
In a key paper, it was reported that the gut microbiota in obese humans and mice differ from those in lean individuals [9].
In order to assess how jnk1−/− mice differ from wild-type mice we analyzed gene expression patterns prior to and following mechanical ventilation.
We have demonstrated that magnocellular cholinergic neurons in nucleus basalis in acute slices from adult mice differ from non-cholinergic magnocellular neurons in several respects, including spiking rates, spike waveforms and after-spike potentials.
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These mice differed from each other by interchanging their H-2 haplotypes in two different genetic backgrounds.
The sensitivities against psychostimulants in orexin/ataxin-3 mice differed from those in orexin KO mice.
In these conditions, the behaviour of TRαAMI/Cre3 mice differed from that of control littermates only in the light-dark box.
The results of the transmission study in TgBoPrP mice differed from those obtained in the case of wild-type mice.
Immunological analysis showed that I/St mice differed from less susceptible A/Sn mice in that they exhibited lower antimycobacterial responses [11], [17] and more prominent inflammatory reactions [11], [16], [18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com