Exact(1)
In parallel with our soft-agar experiments, knockdown of Bim in CXCL12-Luc cells partially restored metastatic potential of these cells, resulting in half of the mice developing hepatic tumors (Figure 8A and C).
Similar(59)
All mice developed hepatic steatosis over 12 weeks, but mice fed the sucrose-palmitate diet accumulated more hepatic lipid than those in the other three experimental groups.
As under catabolic conditions the mice develop hepatic and muscular symptoms [10]-[12] [10]-[12]hesized the same for the kidneys despite the existence of an enzyme wethypothesizedg substhete sameiforithe the long-chain acyl-CoA dehydrogenase (LCAD) [6],[15].
Ob/ob mice develop hepatic copper deficiency.
VHL+/− mice developed hepatic vascular lesions [ 7] and EAF2−/− mice developed PIN lesions [ 15].
As a consequence male mice developed hepatic tumors, while female mice remained tumor free.
Atf6 knockout mice developed hepatic steatosis upon ER stress through regulation of genes involved in lipogenesis [ 24].
HCV core protein-transgenic mice develop hepatic steatosis due to impaired β-oxidation caused by mitochondrial damage [ 2].
When challenged with a high-fat diet, liver-specific Sirt1 knockout (KO) mice develop hepatic steatosis, hepatic inflammation, and endoplasmic reticulum stress [ 5].
NAFLD is often accompanied by obesity, hypertriglyceridemia, type 2 diabetes, and insulin resistance [ 30], and PPARGC1A knockout mice develop hepatic steatosis [ 12].
It is uncertain whether elevated hepatic lipid levels are sufficient to cause factitious lowering of metal levels in ob/ob mice, or whether these mice develop hepatic copper deficiency.
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