Sentence examples for mice developed substantial from inspiring English sources

The homozygous E1-DN mice developed substantial albuminuria.

However, at day 7 the control mice developed substantial bioluminescence corresponding to metastatic tumors.

To this end, we have found that TLR4lps-d and TLR9−/− mice display quite different patterns of lung injury in response to K. pneumoniae challenge, as TLR4lps-d mice develop substantial alveolar leak (as measured by BAL albumin levels) as compared to infected WT animals, whereas TLR9−/− mice tended to be protected against lung injury as compared to WT mice (data not shown).

When compared to other mouse models of diabetes, E1-DN mice develop substantial albuminuria and glomerular pathology.

It has been reported that these double-Tg mice develop substantial Aβ deposits in their brains by 6 months of age (Jankowsky et al., 2004).

The hyperglycaemic E1-DN mice develop substantial albuminuria and histological and structural changes including mesangial expansion, thickening of the GBM, podocyte foot process widening, and altered tubular epithelial cell morphology and proliferation.

Examining the offspring in the F1 and F2 generations after inter-crossing between strains showed that mice with a strong C57BL/6J background developed substantial fibrosis, which was more obvious in male mice whilst mice with the C3Hf/Kam background did not show a response [ 7].

No antidonor Abs were detectable in chimeras treated with Tregs at any time point, whereas control mice (BMT recipients receiving the same regimen without Tregs) developed substantial levels of antidonor Abs at late time points (data not shown).

First, the CAB has developed substantial consensus norms.

Although all mice developed clinical symptoms within three days post challenge, this was not associated with substantial lethality.

On a chow diet, these mice develop spontaneous and substantial hypercholesterolemia with a lipoprotein profile similar to that of human hoFH patients.