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Results show that both WT and nNOS KO mice developed significant CPA.
At the end of the study, the wild-type mice developed significant cardiac hypertrophy (23.6+/-2 23.6+/-2e in heart-to-body weight ratio).
Only WT mice developed significant cortical bone loss after OVX.
We found that Myd88−/− mice developed significant hyperglycemia relative to WT controls upon glucose challenge (Figure 4A D).
We tested this possibility using ELISA assays on individual sera and found that MOMP-vault immunized mice developed significant antibody to MVP (Fig. 6c).
PDGF-AL transgenic mice of line 8 were fertile and their offspring were vital at birth until the approximate age of one and a half month after which most of these mice developed significant skull enlargement and died (Figure 2A).
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TAZ-deficient mice develop significant renal cyst as early as embryonic day 15.5.
These mice develop significant vacuolization (scored 3 out of 5) in the hippocampus, thalamus, hypothalamus, and anterior and posterior cerebral cortex (also called the secondary visual cortex).
In summary, HeN mice develop significant RN following kidney infection.
Thus, homozygous Sod1 D83G/D83G mice develop significant LMN degeneration between 6 and 15 weeks of age, which does not progress.
RESULTS: β-Secretase knockout mice develop significant retinal pathology including retinal thinning, vascular abnormalities and an increase in the age pigment, lipofuscin.
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