Sentence examples for mice developed overt from inspiring English sources

The dose of bacteria was high enough to be detected in the intestine, but not so high that the mice developed overt illness.

None of the mice developed overt diabetes.

Fasting blood glucose and body weight in db mice were significantly elevated relative to controls, and increased over the duration of the protocol as the db mice developed overt diabetes.

In contrast, only 3 of 17 NS mice developed overt leukemia within the same time frame after reinjection with CD22-RTM transfected xenograft cells 2-Tailed Fisherr's exact, P < 0.0001).

Control mice developed overt disseminated leukemia with massive splenomegaly and an average nucleated spleen cell count of 178 ± 60 × 10 (Log10 count: 7.8 ± 0.3) that was significantly higher than the nucleated spleen counts of non-leukemic control NS mice (4.6 ± 0.4 × 10, Log10 count: 6.6 ± 0.4, P < 0.0001) (Fig. 2C).

The female NOD mice develop overt diabetes at the age of 12 wks and the incidence reaches 80% by 25 wks of age.

Most NOD mice will develop severe insulitis by 10 weeks of age, and, in our experiments, a small percentage (<10%) of mice develop overt hyperglycemia by 12 weeks of age [1].

The polycythemia induced by JAK2 V617F was maximal at 3 to 4 months post-transplantation, but tended to decrease with time in both strains, with hematocrit and reticulocyte counts returning to nearly normal ranges by 7 to 8 months after transplantation (Figure 5A), and some mice developing overt anemia.

We have established that sarcolemmal-associated β-catenin is a substrate for Ozz-E3 and that ozz−/− mice develop overt sarcomeric defects, which we have attributed in part to the impaired turnover of β-catenin at the membrane of differentiating myofibers [12].

In particular, females with RTT develop symptoms as young children whereas heterozygous Mecp2-KO mice develop overt phenotypes late on in adulthood and they are generally much milder.

During the acute phase of infection, mice develop overt signs of infection (hunched posture, reduced movement, loss of body weight, piloerection).