Sentence examples for mice develop systemic from inspiring English sources

BAC fxAR121 mice develop systemic and neuromuscular phenotypes, including shortened survival.

The me v / me v mice develop systemic autoimmunity and have a shortened lifespan.

In particular, moribund mice develop systemic mononuclear vasculitis that leads to myocarditis, aortitis and coronary arteritis with intimal proliferation, characteristic of Kawasaki disease.

Foxp3-deficient mice develop systemic autoimmune disease, and evidence from adoptive transfer experiments suggests that this is the direct result of nTreg defect.

The majority of the C. rodentium infected mice developed systemic infection and colitis in the mid and distal colon by day 12. C. rodentium bound to the major secreted mucin, Muc2, in vitro, and high numbers of bacteria were found in secreted MUC2 in infected animals in vivo, indicating that mucins may limit bacterial access to the epithelial surface.

The loss of SIRPα signaling did not affect the numbers of FoxP3+ Treg in the steady-state LP, and SIRPα mt mice developed systemic tolerance normally after feeding protein, a phenomenon that is dependent on Treg cells 1.

Here, we describe MXH10/Mo-lpr/lpr (MXH10/Mo/lpr) inbred mice, which develop systemic swelling of LNs up to 10 mm in diameter, allowing investigation of the topography of LNs and LVs.

The mice, then, develop systemic lupus erythematosus and SS-like disease [ 64].

MRL/Mp- lpr/ lpr (MRL/ lpr) mice spontaneously develop systemic lupus erythematosus (SLE -like diSLE -like

Interestingly, PLA2G3-Tg mice also develop systemic inflammation [ 67], suggesting that the elevated inflammatory state in the vascular wall may have an additional impact on the promotion of atherosclerosis in these mice.

However, despite the block in MZ-B cell development, male BXSB mice develop a systemic autoimmune disease, suggesting that under some conditions low-affinity autoreactive B cells may be redirected toward the follicular B cell pathway [ 107].