Sentence examples for mice develop spontaneous from inspiring English sources

Unlike single Rac1 and Rac3 null mice, double KO mice develop spontaneous epilepsy during postnatal development.

Mice with overexpressed SYN (SYN transgenic mice) develop spontaneous arthropathy.

Bettelli, E. et al. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

Nonobese diabetic (NOD) mice develop spontaneous autoimmune Type 1 diabetes (T1D) that results from the destruction of insulin secreting β cells by diabetogenic T cells.

The tumor suppressor p53 restrains the expansion of carcinogen-initiated cells by inducing cell cycle arrest and apoptosis; accordingly, p53-deficient mice develop spontaneous and chemically induced neoplasms at a much higher frequency than normal mice.

IL10 deficient mice develop spontaneous colitis, suggesting the important roles of IL10 in regulating overactive inflammatory responses (Gomes-Santos et al. 2012).

These transgenic mice developed spontaneous tumors at 40% penetrance.

Mimicking immune tolerance to tumor-associated antigens (TAA) such as HER2/neu, transgenic mice developing spontaneous mammary tumors are strong model systems for pre-clinical vaccine testing.

The Tie2 PPARgamma mice developed spontaneous PAH in RA with increased RVSP, RVH, and muscularized PAs vs. wild type (WT); both genotypes exhibited a similar degree of PAH following chronic hypoxia, but Tie2 PPARgamma mice had more residual PAH compared with WT mice after Rec-RA.

Sei1-null mice developed spontaneous malignant tumors with the same incidence and spectrum as wt mice (Fig. 6A).

Conventionalized AOM-Il10−/− mice developed spontaneous colitis and colorectal carcinomas while AOM-WT mice were colitis-free and developed only rare adenomas.