Sentence examples for mice develop lethal from inspiring English sources

Relb−/− mice develop lethal multiorgan inflammation shortly after birth [26], [27].

Rgn and Gulo KO mice develop lethal scurvy and spontaneous fractures occur in Rgn KO mice.

In the absence of SIRT6 function, mice develop lethal hypoglycemia (Mostoslavsky et al., 2006; Xiao et al., 2010).

Accordingly, BALB/c-TGFβ1 KO mice develop lethal inflammatory hepatitis that was not observed in other genetic backgrounds.

Here, we show that SWR/J mice develop lethal, transplantable myeloid leukemias with dysplastic features after ENU exposure, recapitulating features of the human disease.

Using an intranasally challenged mouse disease model, we found that twenty percent of the mice developed lethal meningitis even though no bacteria could be detected in blood.

A few (less than 10%) of Pdx1-tTA; tet-o-PyMT-IRES-Luc bitransgenic mice developed lethal acinar cell carcinomas in adulthood when the PyMT transgene was induced during embryonic pancreatic development.

As sublethally irradiated NSG mice do not develop lethal thymomas as NOD-scid mice do, we determined whether the SCID repopulating cells from the 10 day culture contain long-term HSCs.

Intriguingly, unlike the COX-deficient mice mentioned above, the Lrpprc heart-specific knockout mice develop a lethal cardiomyopathy, suggesting that COX deficiency may not provide the sole explanation of the phenotype.

PAX1/E2A double-mutant mice develop non-lethal neural tube defects that resemble human malformations [ 36].

In addition, because MMP9 clearly rescues Plg −/− mice from developing lethal inflammatory mass lesions in the colon, we investigated the expression pattern of MMP9 in inflamed colon lesions of Plg −/− mice.