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Post-hoc test on values of S14G-HN-treated male mice detected a significant difference between platform quadrant and opposite quadrant (p<0.05).
Binary analysis of tumor presence (≥1 tumor, n = 113 mice) and absence (0 tumors, n = 125 mice) detected a single modifier locus (LOD = 3.83; Figure 3).
Some of the serotonergic neurons fired rapidly in response to punishments, but not rewards; others fired rapidly when the mice detected a scent that meant that a reward was about to be given.
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Longer exposure of blots from Hp/− mice detected an α-DG species recognized by IIH6 with the molecular weight of ∼150 kDa (Fig. 2E), suggesting that a small amount of intact α-DG also is present.
When a mouse detects a nearby mate, or danger, in the form of disease, it needs to trigger a quick reaction, whether it's an attempt to reproduce or to avoid a nearby sick animal, he says.
Application of ADP led to the generation of adenosine in WT and Entpd3 -/- mice, detected as an increase in measured current at oxidation voltages of 1.0 and 1.5 V. Currents at 1.0 V were then converted to adenosine concentration.
EcSOD protein expression in isolated cardiomyocytes and whole heart from WT and ecSOD Tg mice detected by Western analysis (panel A); Representative Western-blots and quantitative analysis of eNOS expression in whole heart from WT and ecSOD Tg mice detected by Western analysis (n = 3, panel B).
Nevertheless, as seen before in DKO mice, we detected a decreased number of B lymphocytes in the liver of flip−/− mice in comparison with wt mice (wt versus flip−/−, 2357.1 versus 1824.6; P=0.07, NS).
In contrast to the increased number of CD4+ T cells present in tumours of PyVmT/Usp18 deficient mice, we detected a small but significant decrease in splenic CD4+ T cells of Usp18 KO mice (Supporting Information Fig 1B).
We additionally investigated the number of Sialoadhesin (Sn) expressing macrophage like cells in 12 months old PLPtg/PD-1-/ mice and detected a very low amount of positive profiles in both wildtype and PD-1-/ mice.
In normal control mice, we detected a strong signal from the abdomen that was significantly different from the signal in control vector (HSVlac) treated mice, and maximal on day 7.
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