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Reduced density of Toluidine blue staining in CIOA mice demonstrated marked loss of glycosaminoglycans (GAGs) in the cartilage.
Furthermore, experiments using mice demonstrated marked differences in neuroinvasive phenotype that did not correlate with lineage, which suggests that highly and less neuroinvasive phenotypes exist in both lineages (2, 4 ).
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Using three statistical methods, microarray data demonstrated marked changes in the old mouse.
Furthermore, ZSTK474 is suitable for oral administration, and demonstrated marked in vivo antitumor activity in mice grafted with human cancer cells without showing toxicity to major organs [ 29].
Immunofluorescence studies demonstrated marked deposits of IgG and C3 in the glomeruli of vehicle + ASLN mice compared to normal control mice (total intensity score 204 ± 18 vs. 31 ± 8, p <0.005), which were still present in the glomeruli of the Citral + ASLN mice (total intensity score 211 ± 23).
Periostin deficient mice challenged with Aspergillus allergen were significantly more hyperresponsive to acetylcholine than wild-type controls and demonstrated marked increases in systemic IgE responses.
Finally, using a cell type-specific approach, they demonstrated marked mis-expression of genes suggested to be regulated by Zeb1 in a mouse mutant with a mutation in the Zeb1 transcription factor.
The five VPA/divalproex formulations demonstrated marked absorption differences.
However, we observed that a glpX mutant demonstrated marked attenuation.
AR6319 (Ae. albopictus) demonstrated marked CPE.
Analyses by geographical area demonstrated marked heterogeneity.
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