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S. pneumoniae infected mice demonstrated increased collagen deposition at the pleural and subpleural space when compared to saline-treated mice at 14 days.
S. pneumoniae infected mice demonstrated increased collagen deposition at the pleural surface and in the subpleural region compared to saline-treated mice.
Confocal analyses of tissue sections from S. pneumoniae-infected mice demonstrated increased α-SMA expression that colocalized within the pleural and subpleural regions, demonstrating that MesoMT occurred in WT mice by 7 days after pleural infection.
Following sulfur mustard exposure, primary skin fibroblasts from PARP-deficient mice demonstrated increased internucleosomal DNA cleavage, caspase-3 processing and activity, and annexin V positivity, compared to those derived from PARP+/+ animals.
βOGT-KO mice demonstrated increased ER stress and distended ER architecture, and these changes ultimately caused the loss of β cell mass due to ER-stress-induced apoptosis and decreased proliferation.
However, the immunohistochemical staining of frontal cortex from 15-month old knock-in mice demonstrated increased TDP-43 and ubiquitin-positive inclusions.
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Tumor TACs were obtained after i.v. injection of [11C]erlotinib into NSCLC tumor-bearing mice, demonstrating increased radioactivity uptake in erlotinib-sensitive tumors (HCC827 and NCI-H3255) compared to insensitive (QG56) or resistant NCI-H19755) ones.
Concomitantly with the tight skin phenotype at two weeks of age, Tsk2/+ mice demonstrate increased levels of total transforming growth factor beta 1 (TGF-β1) and excessive accumulation of dermal elastic fibers.
In addition, myc overexpressing mice demonstrate increased incidence of tumours (Pelengaris et al, 1999).
In addition, these mice demonstrate increased small intestinal permeability before the onset of colitis.
SHIP1−/− mice demonstrate increased osteoclastogenesis and bone resorption during inflammatory conditions such as arthritis.
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