Sentence examples for mice demonstrate progressive from inspiring English sources

Tyr423His Myoc mice demonstrate progressive degenerative changes in the peripheral RGC layer and optic nerve, with normal organization of aqueous drainage structures [ 101].

Mice demonstrate progressive muscle weakness starting approximately at the age of 6 months.

In the grip strength test, the knock-in mice demonstrated progressive muscle weakness in forelimbs.

Similarly, VMAT2-deficient mice demonstrated progressive non-motor symptoms prior to the onset of motor deficits (Taylor et al. 2009).

MRL/lpr mice demonstrated progressive development of pneumonitis and sialadenitis, which became noticeable at 10 to 12 weeks of age.

We characterized the behavioural phenotype of spontaneous mutant mice modeling CLN6 disease, and demonstrate progressive motor and visual decline and reduced lifespan in these mice, consistent with symptoms observed in neuronal ceroid lipofuscinosis patients.

Both Fas mutated MRL/lpr mice and NZB/W F1 mice are widely used as genetically prone lupus models, which demonstrate progressive nephritis, elevated serum autoimmune antibodies, and immune abnormalities.

We demonstrate progressive behavioural deficits in YG8sR mice, together with significant decreases of FXN and FAST-1 transcripts and frataxin protein expression compared with C57BL6/J (B6) WT and Y47R controls.

Clinical DR is a progressive disease; therefore the rodent model should also demonstrate progressive dysfunction with increasing duration of diabetes.

However, a recent conditional parkin knockout mouse model demonstrated progressive loss of dopamine neurons in a PARIS-dependent pathway [ 128].

With age, however, ATXN2 Q127-mutant mice demonstrated a progressive decline in motor performance.