Sentence examples for mice created using from inspiring English sources
In 1988 Harvard patented mice created using the new techniques.
Harvard and its licensee, DuPont, however, had the rights to any mice created using the new techniques, even ones created by independent labs.
Chimeric mice created using this model also show long-term survival, even if >50% of neurons are respiration-deficient (47).
By contrast, SV40 mice created using the UPII promoter develop muscle-invasive disease (Zhang et al., 1999; Grippo and Sandgren, 2000).
However, in αS transgenic mice created using the mouse prion protein promoter, the ectopic expression of αS in glial cells, especially in astrocytes can result in a more widespread formation of αS inclusion pathology, thus exacerbating the spread of pathological inclusion and injury responses (Fig. 2b).
The first conditional mouse to be generated was a type 1 GD mouse, created using the Mx1-Cre- loxP system, allowing Cre-mediated deletion of a floxed Gba gene upon treatment with polyinosinic-polycytidylic acid (which activates the Mx1 promoter) (Enquist et al., 2006).
Next, Tg mice were created using a 'half-genomic' construct expression vector derived from the mouse Prnp locus (Borchelt et al, 1996; Fischer et al, 1996).
Since the organ-to-body weight ratio is necessary to extrapolate to humans and to create consistent time-activity curves from the obtained average organ activity per volume or gram of tissue, a 'standard mouse' was created using six C57BL-6 mice.
Transgenic HRASG12V mice were created using a promoter from the CNP gene (Patel et al., 2012).
The mice were created using a construct encoding human DDAH I cDNA, a human B-actin promoter, and RNA processing signals from SV40 derived from a modified human agouti expression vector [ 15], called in this work "DDAH mice".
Wild-type and knockout mice were created using embryonic stem cells from the 129P2 strain carrying a gene trap vector and injected into C57BL/6 blastocysts, as previously described (Calcraft et al. 2009).
