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Alternatively, while zebrafish that lack norepinephrine are healthy, mice containing this modification die early in development.
Mice containing this knock-in construct were generated using standard ES technology, and the resultant mice were bred to homozygosity.
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In this case, DO mice containing the C57BL/6J, CAST/EiJ, or PWK/PhJ alleles at the QTL on chromosome 1 have lower neutrophil counts than mice containing the other five founder alleles.
This study aimed to generate mutant mice containing the Acvrl1 gene flanked with LoxP sequences to allow conditional deletion of Acvrl1 by the LoxP/Cre system.
In the cell cultures and living mice containing the ribozyme sequence, protein production dropped to nearly undetectable levels.
Genotyping PCR demonstrated that eggs from mutant mice contained the Separase mutation (Figure 1D).
The mice contained the fusion protein of PER2 and luciferase.
For this, we generated transgenic mice containing a loxSTOP lox (LSL) codon upstream of the PrRP gene.
In this study, we test our hypothesis in the FKRP mutant mice containing P448L mutation which is associated with CMD in clinic.
The Mouse ES Cell & Transgenics Core Facility specializes in assisting researchers with the design, generation, maintenance, and analysis of mice containing designer mutations.
Transchromosomic mice containing two or four copies of the MAC were generated by breeding.
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