Sentence examples for mice containing both from inspiring English sources

The use of transgenic mice containing both fluorescent microglia/macrophages [24] and neurons [25] enables us to correlate mutation-induced changes of microglia/macrophage function with the progressive axonal degeneration in the CNS or PNS, respectively.

In bigenic mice containing both Tet-Bax and nestin-rtTA constructs, a short-term Dox treatment (three weeks, 2 mg/ml) induced the expression of EYFPBax proteins in the DG (Figure 1D, t5 = −12.1, p<0.001) but not in the SVZ (Figure 1D, t5 = 0.28, p>0.78).

Groups of six to seven mice, containing both males and females, were used for the experiments.

Kuraoka and colleagues established chimeric mice containing both wildtype BM and BM from Aicda-deficient (the gene encoding AID) mice (Aicda KO) [ 45].

To produce conditional Tg mice in which DNMT3A2 and DNMT3L expression is induced during gametogenesis, female 2lox mice were crossed with FVB-background Vasa-Cre male mice (purchased from the Jackson Laboratory, Maine, USA) (45), and double Tg mice containing both 2lox and Vasa-Cre alleles were generated.

Chimeric males (mice containing both cells from the microinjected ES cell and the host embryo) were mated with C57B6 females and in cases where the injected recombinant ES cells had contributed to the germ line of the chimeric mouse, the mating resulted in heterozygous (HT) 129/Sv/C57B6 offspring with respect to the target gene.

Fig 1c shows that agouti F1 female mice contained both the mutant (paternal) and wild type (maternal) hprt alleles.

The ascitic tumours formed by intraperitoneal injection of nude mice contained both anaplastic rat cells similar to Rama 900 and mouse mesothelial-like cells similar to Rama 950.

We developed a double transgenic mouse containing both the HLA-DR1 transgene and an HLA-DR1-restricted collagen-specific TCR in order to obtain large numbers of antigen-specific T cells that can be used for immunologic studies.

Moreover, mice chimaeras containing both wild-type and SOX9-null cells develop normally, but there is no contribution by the SOX9-null cells towards cartilage formation [ 11].

Primary mouse cultures containing both excitatory and inhibitory neurons have been shown to increase transient sizes as well as interburst intervals when GABAergic activity is blocked (Robinson et al., 1993).