Sentence examples for mice containing a from inspiring English sources
There are also mice containing a part of 9-year-old Michael Feeney — a cancerous tumor extracted from his lungs.
We recently showed that chimeric mice containing a human chromosome 21 (Chr 21) exhibited phenotypic traits of DS, including CHD.
Primary MEFs were derived from OG2+/−/ROSA26+/− (OG2) mice (containing a transgenic Oct4-GFP reporter) then transduced with retroviral vectors expressing Oct4, Sox2, Klf4, and c-Myc.
This effort resulted in the identification of compound 4a, which had a binding IC50 of 4.0 nM and was shown to reduce blood glucose levels at 3 mg/kg in glucagon-challenged mice containing a humanized glucagon receptor.
Thus, many of the clinical and pathological features of Gerstmann-Straussler-Scheinker syndrome are reproduced in transgenic mice containing a prion protein with a single amino acid substitution, illustrating that a neurodegenerative process similar to a human disease can be genetically modeled in animals.
Pol λ −/− [14] and pol β +/− [15] mice were previously generated from embryonic stem cells after targeted gene knockout in mice containing a C57BL/6 background.
To investigate the consequence of overriding uniparental inheritance, we generated mice containing an admixture (heteroplasmy) of NZB and 129S6 mtDNAs in the presence of a congenic C57BL/6J nuclear background.
Christophorou et al. developed mice containing an inducible wildtype p53 allele on a p53 null background [14].
Experiments by the Evan laboratory performed with mice containing an inducible wildtype p53 allele showed that after a carcinogenic insult, p53 could delay cancer if activated several days after the insult rather than during the insult.
First, mTORfl/flCol2-rt-TA-Cre mice were generated by mating mice containing an mTOR gene flanked by LoxP sites (C57BL/6-mTORfl/fl, Jackson Laboratory) with C57BL/6 Col2-rt-TA-Cre transgenic mice as previously reported.
b Pleural lavage fluid from S. pneumoniae infected PAI-1−/− mice contained a significantly higher percentage of neutrophils than identically treated WT mice.
