Sentence examples for mice contained human from inspiring English sources
26 mice contained human endometrial-like tissues were examined by histological analysis of tissue sections at different indicated time points.
Of the 16 mice treated with PBS, only 7 engrafted T cells and one of those 7 also engrafted B cells, overall 43% of the mice contained human lymphocytes.
To address this important caveat and to examine effects on tissue architecture in a valid setting, it was decided to construct transgenic mice containing human genes for CEA and CEACAM6.
wt: wild-type C57BL/6 mice, Tg: hemizygous transgenic mice containing human CYP2C18&19.
Transgenic mice containing human SMN2 and the mouse Smn knockout are as described previously (41).
When the experiment was extended to 21 days, investigators observed a significant concordant reduction in tumor mass. 2 Axitinib was initially evaluated in vivo in mice containing human renal cell carcinoma (RCC), melanoma, and colorectal cancer xenografts, and it inhibited tumor growth in a dose-dependent fashion for all three histologies.
HCV infection also correlated with high level of endogenous CES1 in transgenic mice containing human-mouse chimeric livers.
Cerione and his colleagues are currently testing glutaminase inhibitors in mice that contain human breast cancer tumors, using a system that was originally developed by their collaborator, Alana Welm, while she was at the Huntsman Cancer Institute in Utah.
To control for genetic background, Tg-Mc1re, are littermates of the Mc1re mice, which contain human MC1R gene on a bacterial artificial chromosome [28], leading to rescue of the non-functioning MC1R such that the yellow mutant pigmentation becomes a normal agouti coat colour as previously described [28].
Xia, T. S. et al. Bone metastasis in a novel breast cancer mouse model containing human breast and human bone.
In this study we assessed, for the first time, the use of transgenic, chimeric mice containing functioning human hepatocytes as an alternative for modeling the in vivo interaction of P. falciparum parasites and human hepatocytes.
