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There was a slower progression of disease in mice consuming the high ω-3 diet than in mice consuming the high ω-6 diet at each time point.
The prostate of mice consuming the high ω-3 diet weighed significantly less than prostate of mice consuming the high ω-6 diet at 24 and 40 weeks (by t-test at P < 0.05).
The expression level of AR in DL was significantly higher in mice consuming the high ω-6 diet than in mice consuming the high ω-3 diet at 40 weeks but not at 24 weeks.
Similar gross and histological differences between the two groups were observed here as with our previous study, with an overall significant survival benefit achieved for mice consuming the supplemented diet [ 2, 13].
The observation that mice consuming the Sutherlandia or elderberry diets showed significantly less microglial activation as compared with the ischemic brains of mice consuming control diet supports the capacity of these diets to mitigate neuron damage and microglial activation.
Mice consuming the high-fat diet developed larger tumors than did mice fed the low-fat diet; moreover, alcohol ingestion increased the final tumor volume in both dietary groups.
Similar(54)
Because obese people in western cultures where liver disease is prevalent typically consume a diet that contains high amounts of saturated fat, we hypothesized that mice consuming SAFA would exhibit the greatest degree of NASH.
The water intake mirrored the food intake with the deletion mice consuming more water as well (data not shown).
There was no difference in food intake between the mice consuming quinine supplemented diet and those consuming control diet.
Nevertheless, the diurnal distribution of feeding was altered between the mice, with knockout mice consuming a greater amount of food during the light phase of the day.
Indeed, it is already known that genes involved in mitochondrial OXPHOS proteins expression were upregulated in mice consuming KO as revealed from the transcriptomic analysis [ 12].
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