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We measured the frequencies and the durations of aggressive attacks by resident mice against the unfamiliar intruder mice, consisting of biting, clinch, lateral threat and keep down.
In this case, lacZ acts on a molecule injected into the mice, consisting of galactose linked to luciferin, a luminescent protein naturally produced by fireflies.
An experiment was designed to automatically assess the relative level of social interaction during encounters involving trios of inbred mice consisting of two familiar cage mate males plus an unfamiliar third male.
These mice are an outbred strain that was derived in 1926 from an original colony of non-inbred Swiss mice consisting of 2 males and 6 females.
We compared mice treated with tamoxifen (activating Cre recombinase) to control mice consisting of untreated K14CreERxRac1flox/flox mice or litter mates that were Cre negative with and without tamoxifen.
Cohort B consisted of 7 wt, 9 het, and 8 Atxn2 ko mice consisting of 3 wt female, 5 het female, 3 female Atxn2 ko, 4 wt male, 4 het male, and 5 Atxn2 ko mice.
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Consistent with this role, the ME mucosa of untreated mice consisted of a simple, squamous epithelial monolayer with a minimal stroma.
Findings in Phox2b27Ala/+ knock-in mice consisted of unstable breathing with apneas, absence of the ventilatory response to hypercapnia, death within a few hours after birth, and absence of the retrotrapezoid nucleus (RTN).
Cohort A mice consisted of 22 wt and 16 Atxn2 ko.
Control mice consisted of identically treated littermate wild-type mice for both transgenic models.
After seven weeks of engraftment, at least 80% of the leukocyte population of all mice consisted of donor-derived cells, indicating extensive engraftment (data not shown).
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