Left ventricular mass and end diastolic dimension were unchanged in Emilin1−/− mice, consistent with the absence of a primary cardiomyopathy.
CaIX staining was reduced in Hif1a+/− mice, consistent with a reduced HIF-1 response in these HIF-deficient mice.
Light-flicker treatment induced gamma oscillations and reduced Aβ levels in ageing wild-type mice, consistent with a physiological role for gamma stimulation in regulating Aβ metabolism.
In food-deprived mice the lipidation of LC3 was impaired and abundance of p62 increased in aorta of aged compared to young mice, consistent with dysfunctional autophagy induction.
BALB/c mice were more sensitive to these toxicities than C57BL/6 mice, consistent with the higher in vitro functionality of BALB/c T cells.
Immunohistochemical staining of bromodeoxyuridine (BrdU) incorporation (Fig. 5e) showed intense staining of luminal epithelium of vehicle treated mice, consistent with high rates of proliferation to reepithelialise the shed endometrial surface.
The average tumor to background ratio after signal calibration for cRGD-Cy5.5 injection is approximately 2.43±0.95 at 1 h and 3.64±1.38 at 2 h (N=5 mice), consistent with data obtained with a cooled charge coupled device camera.
3-NT gradually increased in all strains during HBO(2) but accumulation was slower in nNOS mice, consistent with less ONOO production.
After introducing this enzyme into mouse zygotes, efficient base editing was observed in both embryos and live born mice, consistent with Kim et al.'s results.
In the current study, injection of 50 nm or larger GNPs, however, did not lead to the death of mice, consistent with the observation that the cell membrane prevents the passage of particles larger than 200 nm.
The oral LD50 was approximately 1200 times higher than ip-treated mice, consistent with previous data [3], [26], [27].
