In an experiment at Johns Hopkins, in 2010, mice were confronted with two levers, one that dispensed a treat after being pressed only once, another that required fifteen presses before it released a similar snack.
These findings indicate an increased arousal/vigilance state when mice are confronted with highly arousing stimuli, such as a novel social interaction (23), shown to trigger PFC activation (24).
For that purpose, we used a social interaction task in which a previously isolated male mouse was confronted with a novel male C57BL/6 mouse in a novel, large environment.
To test this, laboratory mice (C57BL/6) were confronted with a short-term challenge of CpG-ODN followed by repeated immunization with bovine serum albumin (BSA) and alum.
Similarly, we can test avoidance behavior by determining to what extent motivation mice are de-motivated when confronted with an aversive situation, such as an emerging obstacle.
Humans may or may not be intrinsically more intelligent than cats, he wrote, but when a cat is confronted with a mouse its behavior is likely to be demonstrably more intelligent.
This hypothesis appeared consistent with later experiments showing that in vitro fetal thymic organ culture some DP cells from female HY-TCR transgenic mice could become CD8αα T cells when confronted with HY antigen [5].
Confronted with a severe breeding deficiency of the NHERF1-mutant mice, we examined in a prospective study the age of NHERF1-mutant females at their first pregnancy.
The postoperative intensive care and analgesia regimens described here may be useful for others confronted with similar difficulties when implanting probes or conducting major surgery in mice.
Recent studies have shown that mouse embryonic dental epithelium possessing odontogenic potential is able to induce the formation of a bioengineered tooth crown when confronted with postnatal mesenchymal stem cells of various sources.
