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To date, evidence linking gap junction remodeling with ventricular dysfunction has been correlative, with the exception of studies done on chimeric mice, composed of variable mixtures of Cx43-null and wild-type cells throughout all tissues of the body [32].
In this study, we provide the so far most comprehensive geographic sampling of genetically characterized African pygmy mice composed of 657 Nannomys individuals from most parts of sub-Saharan Africa.
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Because white-footed mice composed >79% of all captures, we focused on this species.
Four groups of newborn mice, each composed of 10 mice (five males and five females), were used for evaluating molecular biomarkers, including bulky DNA adducts, oxidative DNA damage, and miRNA expression profiles in the lung, as follows.
We analyzed the behavior of 17 groups of mice, each composed of four adult mice in an arena resembling an ethologically relevant context that has an interesting environment for exploration (see 'Materials and methods').
Groups of 10 mice composed Group 1 that were maintained till 10 weeks following infection, other 10 mice composed Group 2 that were maintained till 14 weeks of infection.
Similarly, the LN of 4-times-exposed mice was composed of 30.3% CD11b+ cells, as compared to mosquito-naïve mice, for which 20.6% of cells were CD11b+ (Fig. 5A; p<0.05A.
Unless specified, groups of mice were composed of 2 animals.
The above results suggest that the lung tumors in the p53(273H) transgenic mice are composed of a mixed population of cells.
The common pattern of C57BL/6 mice was composed of some antigens to which there were strong and consistent antibody reactivities and of other antigens to which there were much weaker reactivities (Figure 2).
The ancestral karyotype of the pygmy mice was composed of 36 acrocentric chromosomes [ 17, 92], but the wide spectrum of mutational mechanisms modified the chromosomal constitution.
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