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There were 1613 DEG in CIA Nampt+/+ mice compared with non-CIA control Nampt+/+ mice and 1778 DEG in CIA Nampt+/− mice compared with CIA Nampt+/+ mice.
Finally, 24 hr lesion volumes were significantly reduced in knock-out mice compared with wild types.
Lymphocytes are increased in CD73−/− mice compared with wild-type mice in 70% hyperoxia.
(e) Upstream regulator analysis in gene expression data of S30 mice compared with CT mice.
We determined fold changes for two comparison groups: (1) CIA Nampt+/+ mice compared with non-CIA control Nampt+/+ mice, and (2) CIA Nampt+/− mice compared with CIA Nampt+/+ mice.
HFD-induced cardiac hypertrophy and contractile reserves were ameliorated in cardiomyocyte-specific miR-451 knockout mice compared with control mice.
However, neutrophil and monocyte infiltration were decreased in the lungs of PF4-/ mice compared with B6 control mice.
The serum levels of the CII antibody were decreased significantly in Nampt+/− mice compared with Nampt+/+ mice (Fig. 1b).
Importantly, the survival rate was significantly improved by BLM + PM014 (200 mg/kg) mice compared with BLM-only mice.
EPA has a different effect on body weight in ob/ob mice compared with high fat diet-fed mice.
Expression levels of Nrg1 were significantly lower in cardiac ECs prepared from Bmx/CA mice compared with Ctrl mice.
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