Sentence examples for mice clearly indicate from inspiring English sources

Despite this caveat, our studies in NOD and C57BL/6 mice clearly indicate that IL-21 reduces T cell survival and suggest that it might promote lymphopenia to drive homeostatic proliferation.

More importantly, unchanged hyperglycemia, hyperinsulinemia, pancreatic insulin content and ITT response in pair-fed mice clearly indicate an absence of effect by caloric restriction on insulin sensitivity, thereby implying a possible dissociation between anorexic and insulin-sensitizing effects of Boc5 [27].

Thus, although Sod1 null mice clearly indicate a susceptibility of specific tissues to the effects of a loss of SOD1 function, any discussion in the context of ALS must look at phenotypes that arise in Sod1+/− animals (Supplementary Fig. 1) that retain 50% SOD1 activity (Reaume et al., 1996) and so mimic the physiological levels described in patients with SOD1 familial ALS.

The results of generating KO mice clearly indicated the site specific and dependent mutations in newborns mediated by tru-RGNs compared to std-RGNs controls.

A comparative analysis between APPYG/YG, APPTA/TA and control mice clearly indicates steady-state APP phosphorylation predominantly occurs on Thr668 and not Tyr682 in normal brain (Fig. 2D).

However, NKDCs from V α14 TCR Tg mice presented increased IFN- γ production compared with WT mice, clearly indicating that NKT cells are required for NKDC function.

The phenotype of B7h-deficient and ICOS-deficient mice clearly indicates that they are a unique receptor ligand pair that have a positive costimulatory effect.

The lack of skin pathology in ATGL-deficient mice clearly indicated that CGI-58 has an ATGL independent function in the skin and possibly other tissues.

Diminution in gamma amino butyric acid (GABA) levels in the brain of extract the treated mice compared to vehicle the treated mice clearly indicated the involvement of GABAergic mechanisms in the anticonvulsant activity [ 26].

The reduction of swelling in SNS-gp130−/− mice clearly indicates that sensory neurons are involved in the early development of inflammation and that IL-6 exerts part of its proinflammatory role by activating sensory neurons.

It has been found that damaged areas and serum alanine aminotransferase/aspartate aminotransferase levels are significantly increased in these two animal models post-DEN injection and that that necrotic response is also much stronger in EGFRΔhep and EGFRΔMx mice, clearly indicating that expression of EGFR in hepatocytes is required for hepatoprotection.