Active immunization with the chimera protected all the mice challenged with 45 X LD50 of abrin.
These C5a-receptor-deficient mice challenged with sub-lethal inocula of Pseudomonas become superinfected with secondary bacterial strains.
Macrophages were therefore involved in liver damage observed in Ripk1LPC-KO mice challenged with poly I C.
Figure 9: The phenotype of auditory supporting cells of Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2
Moreover, therapeutic administration of m27f completely prevented infection-related mortality of mice challenged with a lethal dose of HSV-2.
Also, passive transfer of antibodies raised against the chimera rescued all mice challenged with 50 X LD50 of toxin.
Logically designed vaccination induced multi-functional CD8+ T cells and provided complete sterilising immunity of mice challenged with TC1 cells.
Morphine-dependent mice challenged with naloxone reliably displayed a profound withdrawal syndrome, consisting of jumping, paw tremors, diarrhea, and weight loss.
In contrast, all 15 mice challenged with untreated HSV-2 died.
Among mice challenged with intracerebral tumors, this resulted in an approximately 600% increase in the median survival time (>300 d, P < 0.0016), relative to control values.
5. Mistry N, Thomas A, Kaushik SS, Driehuys B. Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine, Magn Reson Med, in press.
