Sentence examples for mice causes lethal from inspiring English sources

Likewise, the administration of the agonistic antibody to Fas in mice causes lethal liver failure through massive hepatocyte apoptosis [35].

Here we report that specific ablation of Dido3 function in mice causes lethal developmental defects at the onset of gastrulation.

Mutations in hydin in hy3 mice cause lethal communicating hydrocephalus with early onset.

Mutations in the hydrocephalus-inducing gene, hydin, in hy3 mice cause lethal communicating hydrocephalus with early onset [ 6, 7] and the corresponding region within human chromosome 16 is also associated with congenital hydrocephalus [ 8].

Knockout of the PDGF-A gene in mice causes a lethal emphysema-like phenotype due to failure of myofibroblast development and subsequent formation of alveolar septum [ 40, 41].

Subsp. novicida is highly attenuated for humans, and is rarely isolated, but causes lethal disease in mice [9], [10].

In addition, the Sterne strain has been widely used in both in vitro and in vivo studies of anthrax infection as it causes lethal disease similar to the encapsulated B. anthracis strain in mice [11].

Cytokinesis through incompletely segregated chromosomes causes lethal DNA damage.

ZO-1 deficiency in mice causes an embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells [31].

The mesenchymal defect in the liver of Lhx2-/ mice cause a lethal anemia, which is cell non-autonomous since the Lhx2-/ hematopoietic cells appears to be normal [ 17], suggesting that the mutant microenvironment is unable to support hematopoietic development.

All extracts that were administered orally in a single dose of 2000 mg/kg to the laboratory bred Swiss albino mice caused no lethal effect within 24 h of the observation period.