Sentence examples for mice carried expanded from inspiring English sources

Both Sca1154Q/2Q and Sca7266Q/5Q mice carried expanded CAG repeats in the respective endogenous gene and faithfully recapitulated the phenotypes of SCA1 and SCA7, respectively.

Additional support came later from studies in which overexpression of Mbnl1 in mice carrying expanded CTG repeats reversed DM1-like phenotypes (Kanadia et al., 2006).

The expanded CAG repeat per se does not affect the functional properties of the channels in SCA6 KI mice carrying expanded CAG repeats in the Cacna1a locus (5, 6).

Briefly, OG2 mice carried Oct4 promoter driving GFP expression mated with 129 mice.

The generation of transgenic mice carrying the human genomic DM1 region with expanded repeats of either ∼500 CTG (DM1 mice; displaying mild DM1 phenotype) or 20 CTG (normal; do not develop DM1 phenotype) has been described previously (Gantelet et al., 2007; Seznec et al., 2001).

In a 2006 study, researchers at Washington University, in St . Louis transferred gut microbes from mice carrying a mutation that caused them to be obese to mice lacking the mutation.

The long-lived Ames and Snell mice carry natural mutations that make them deficient in growth hormone.

Offspring of these mice carry these mutations.

Finally, a recent study using knock-in Hdh (Q111) mice, which carry an expanded polyglutamine stretch in the mouse huntingtin protein, has also observed altered DG neuronal maturation along with increased anxiety-like phenotypes [ 143].

Mouse lines carrying the expanded Rep1-261 bp allele showed the highest total SNCA concentration (measuring human and mouse variants, i.e. 6.17 ± 2.53 ng/µl homogenate), followed by lines that carry the protective Rep1-259 bp genotype (5.63 ± 4.74 ng/µl), followed by those carrying the Δ-Rep1 allele (4.74 ± 2.02 ng/µl) (Supplementary Material, Fig. S3B).

Each aircraft carried an expanded crew of up to 14.