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The authors demonstrated that tauP301S expression in the neurons of mice can induce senescence in neuron-supporting cells called glia.
Altogether, we have demonstrated here that prolonged high tTA2 expression in responder mice can induce Ptetbi re-activation, possibly due to the counter-silencing effects of the transcriptional activator [30] [32].
We investigated whether the delivery of N SRS nanostructures with the mucosal adjuvant LT R192G) to adult BALB/c mice can induce protective immunity against a viral challenge with the human RSV-A2 strain.
IL-10 excreted by transfected Lactococcus lactis in the lumen of the intestine of mice can induce IL-10 production by cells of the Peyers patch and prevent allergic sensitization to food [33].
Natural and experimental infection with H. hepaticus in certain immunodeficient mice can induce inflammatory bowel disease [ 10, 11].
However, it was reported that transfer of splenocytes from arthritic mice to SCID mice can induce arthritis [ 37].
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Adenoviral-mediated transfer of TGF-β o the neonatal rat lung or overexpression of TGF- β between postnatal day 7 and day 14 in the mouse can induce histological changes analogous to those seen in BPD [ 19, 39].
Knockout of tmem59 in mouse brain can induce expressional changes of 627 genes in neonatal mouse NSCs.
Tozer et al. recently showed that mouse VEGF188 can induce narrow microvessels with the greatest microvessel length, resistance to hemorrhage and resistance to antiangiogenesis agent therapy, but is associated with tumor vascular maturity [34].
Therapeutic activation of stress response genes such as TP53/ p53 (Trp53 in mouse models) can induce autophagy in addition to apoptosis.
Indeed in mice, LPS stimulation can induce Hif1 activation in lung neutrophils [ 44].
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