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The introduction of mammal predators such as feral cats, rats, mongooses and even mice can have disastrous results for ecologically naïve seabirds.
These cells show frequent rearrangement of the Vγ1.1 variable gene segment to the Jγ4 joining segment and of Vδ6.3 to Jδ1 and, depending on the genetic background of the mice, can have oligoclonal or polyclonal junctional sequences [45], [46].
It is well documented that transgenic mice can have compensatory changes in gene expression, so it seems plausible that alterations in the expression of genes unrelated to 5-HT synthesis could contribute to the failure of dexfenfluramine to produce PAH in female Tph1 mice.
In this respect, Schweizer and coworkers [30] further clarify how different inbred strains of mice can have very different vulnerabilities to the chronic mild stress model of depression in both behavioral and physiological parameters, thus offering an invaluable tool to understanding G×E interaction in stress-induced disturbances.
Thus, although Fmr1 KO mice can have offspring, it also led us to further reveal whether FMRP-miR-383 double downregulation in human testis may affect spermatogenesis.
Indeed, although mice can have as many as 10 to 12 pups in a litter, inbred strains are much less prolific, with litters often limited to 4 to 6 pups.
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A single mouse can have a tumour with different histological components but this considerable intra- and inter-tumour heterogeneity recapitulates that seen in the human disease.
Top-tier stars, like the Disney Princesses and Mickey Mouse can have very long queues, but there are ways meet more stars in less time.
Rapamycin extends lifespan in mice, but can have a number of undesirable effects that may ultimately limit its utility in humans.
Our in vivo data are limited to the mouse-recipient strain, which we have been using for this study (Nod/Scid mice), and we are aware that the use of different mouse recipients can have an impact on the tumour-initiating capability of injected cells (Quintana et al, 2008).
One is a multi-button mouse that can have several keys mounted on it [7].
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