Sentence examples for mice by stimulating from inspiring English sources
In the past few years, Weissman's lab showed that blocking CD47 with an antibody cured some cases of lymphomas and leukemias in mice by stimulating the immune system to recognize the cancer cells as invaders.
We have found that CB3 triggers autoimmune disease in susceptible mice by stimulating elevated levels of proinflammatory cytokines from mast cells during the innate immune response.
Bacterial flagellin protein protects rotavirus-infected mice by stimulating cytokine production.
In addition, Cthrc1 stimulates osteoblast proliferation and differentiation and increases bone formation rates, suggesting that Cthrc1 prevents cancellous bone loss in ovariectomized mice by stimulating osteoblastic bone formation.
FGF21 improves hepatic steatosis and insulin sensitivity in obese mice by stimulating lipolysis and fatty acid oxidation and reducing gluconeogenesis (Xu et al., 2009a).
In addition to blocking cell proliferation, doxorubicin induces renal fibrosis in mice by stimulating production of collagen (Lee and Harris, 2011).
Together, the findings indicate that under normal conditions, ENT1 makes the mice drunk by stimulating the adenosine receptors, which then slows down their drinking.
Activation of CAR also induces a strong proliferative response in mouse liver by stimulating cyclin D1, which is mandatory for cell-cycle progression in proliferating hepatocytes, suggesting that CAR agonists could also be potentially useful to stimulate hepatocyte proliferation after liver resection.
This idea was also exploited to protect mice from T1D by stimulating proliferation and rapid deletion of self-reactive CD4+ T cells in LNs when mice were treated with ERY1 conjugated to T1D antigens, but not when soluble T1D antigens were administered.
Notably, and as in other species, ET-1 increased intracellular calcium concentration in mouse Ml CCD cells by stimulating both release from intracellular stores as well as nifedipine-sensitive calcium entry [ 15].
Thus, although the proliferative response of mutant bone marrow cells to G-CSF is reduced, the increased neutrophil production observed in STAT5−/− mice is recapitulated ex vivo by stimulating the cells with appropriate G-CSF concentrations.
