Sentence examples for mice by manipulating from inspiring English sources

The researchers said they have speeded up and slowed down the rate of ageing in laboratory mice by manipulating chemical messengers that affect the hypothalamus, which is known to play a fundamental role in growth, development, reproduction and metabolism.

Importantly, these data show that varying degrees of increased locomotor activity (in other words, "exercise") can be elicited and maintained in mice by manipulating the schedule of reinforcement.

Researchers have routinely generated new strains of mice by manipulating mouse embryonic cells, and some aspects of this technology may prove useful for improving human embryonic cells.

He notes, however, that other attempts to stimulate bone growth in mice by manipulating cell signaling proteins have produced denser than normal bones and he's surprised that Helms's team didn't see the same.

Such a discovery opened the possibility to create numberless models of human diseases, and related mutant mouse strains by manipulating the genome in ESc.

Our findings are consistent with current models in which bRG is proposed to play primary roles in cortical surface area expansion and folding (Lui et al, 2011; Borrell and Reillo, 2012; Kelava et al, 2012) and complement a recent study inducing gyrification in the mouse cerebral cortex by manipulating a novel nuclear protein affecting BPs and bRG amplification (Stahl et al, in press).

The initial transformation by EWS/FLI-1 and reversal by KRAB/FLI-1 were similar for both mouse and human genes and demonstrate that the generation of a mouse model for this disease by manipulating the mouse genome is appropriate for elucidating the mechanisms and validating novel therapeutic strategies.

Many transgenic mouse models have been generated by manipulating growth factors and their receptors, cell cycle regulators, signal transduction pathways, cellular differentiation, oncogenes and tumor suppressor genes.

Some conflicting results have been obtained by manipulating the mouse β-catenin gene with various Cre deleter transgenes, most of which are active in multipotent progenitor cells.

The concept of the second touch hypothesis generates many sub-hypotheses that can be tested by manipulating the mouse genome in a cell-specific fashion.

We tested this hypothesis using our in vivo mouse model for demyelination and remyelination, by manipulating the levels of Sema3A or 3F using recombinant protein injected into demyelinated lesions or by using a transgenic mouse with reduced Sema3A expression.