Sentence examples for mice by immunization from inspiring English sources

They found that increasing T cell numbers in the mice by immunization with non-specific activators of the immune system, such as mycobacterial cell wall constituents (e.g. complete Freud's adjuvant), protected NOD mice from developing diabetes, indicating a correlation between increased T-cell numbers and disease protection.

Experimental autoimmune encephalomyelitis was induced in DNA-vaccinated mice by immunization with proteolipid peptide (a.a. 139 154).

The induction of EAU in C57BL10.RIII mice by immunization with IRBP peptide161 180, CFA and PTX is well documented [1] [5], [12], [15].

To this end, we induced EAE in C57Bl/6 wildtype mice by immunization with MOG35 55 peptide followed by CpdA therapy using both the intermediate and the low dose of CpdA following the same protocol as in the previous experiments.

MOG EAE induction: EAE was induced in 6 7 week old female C57BL mice by immunization with an emulsion containing 300 μg of purified MOG peptide (MEVGWYRSPFSRVVHLYRNGK, corresponding to residues 35 55) in PBS and an equal volume of complete Freund's adjuvant containing 5 mg H37RA (Difco).

EAE was induced in groups of five 6 10 week old female C57BL/6 mice by immunization with 200 µg of myelin oligodencrocyte glycoprotein (MOG) petide (p) 35 55 (BioSource International, CA) in an emulsion with Complete Freund adjuvant (CFA) containing 4 mg ml−1 of heat-inactivated Mycobacterium tuberculosis H37Ra (Difco Laboratories, MI).

It has been induced in a variety of animals such as rat and mouse by immunization with a number of antigens including interphotoreceptor retinoid-binding protein (IRBP), the soluble retinal antigen [18] or peptides derived from these autoantigens.

Additionally, both Th17 cells and IL-6 have been shown to participate in the pathogenesis of experimental auto-immune myocarditis (EAM; Eriksson et al, 2003; Yamashita et al, 2011), which can be triggered in the mouse by immunization with α-cardiac myosin peptide (Pummerer et al, 1996).

To further verify that Stat6 is the downstream target of Cbl-b in T cells, we performed adoptive transfer of naive CD4+ T cells from WT, Cblb−/−, Stat6−/−, and Cblb−/− Stat6−/− mice into BALB/c nude mice, followed by immunization with OVA in alum and challenge with an aerosol form of OVA.

To define whether IL-10 signaling was critical for the maintenance of Foxp3 expression in Tregs, CD4+RFP+ T cells from Wt and Tg Thy1.1 mice were sorted and transferred to Thy1.2 Wt mice, followed by immunization with CII and CFA.

In contrast to immunocompetent mice, protection by immunization with CMT.TAP1,2/Kb cells was not observed in a nude mouse model that lacks antigen specific T cells (data not shown).