Moreover, abrogation of endogenous IL-28 cytokine function in IL-28Rα−/− mice exacerbated allergic airway inflammation by augmenting Th2 and Th17 responses, and IgE levels.
The controversial role of T lymphocytes in ALS was resolved by our demonstration that their presence in mutant Cu2+/Zn2+ superoxide dismutase (mSOD1) ALS mice plays an endogenous neuroprotective function by augmenting the protective potentials of microglia and attenuating their toxic responses (Beers et al., 2008).
These results suggest that one mechanism by which exogenously administered rhBCL2 or rhBCL2A1 protects tissue against I/R-induced apoptosis is by augmenting increased expression of endogenous mouse BCL2.
Wolf, E, Diaz, EJ, Hollis, AN, Hoang, TA, Azad, HA, Bendt, KM, Griffiths, RC, and Sparks, MA. "Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice". American Journal of Physiology.
The more relevant question is therefore, whether studying mice in a standard, non-enriched generates false positives by augmenting the chance of therapeutic effects secondary to HD pathology.
Sundaresan, N. R. et al. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice.
However, PECs might paradoxically contribute to the deterioration of glomerular function by augmenting scarring and crescent formation under certain circumstances in man and mouse [ 21].
Instead, it adds more value by augmenting traditional systems.
The environmental mycobacterium, M. vaccae has been used in mouse models to support the contemporary hygiene hypothesis that non-pathogenic microorganisms reduce allergy associated T helper (Th 2 responses and inflammatory diseases by augmenting regulatory T cells.
It mediates this role by augmenting tumoral apoptosis.
