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We have developed a radiolabeled murine monoclonal antibody targeting RAGE for in vivo imaging of RAGE expression and have shown focal uptake of this probe in atheroma in apolipoprotein E-deficient (apoE−/−) mice both with and without diabetes [16].
Importantly, deposits of PS129-α-synuclein were present in more than 90% of the neurons in which caspase 9 was activated in hA30Pα-syn mice both with (92.0%±3.2) and without Parkin (96.0%±3.1; p = 0. 4).
However, the consequences of loss of XPA-1 appear more severe in C. elegans compared to mice, both with respect to transcriptional regulation and lifespan.
The main finding of the present study was a disjunction between leukocyte adhesion and vascular leakage; leukocyte rolling and adhesion was increased in septic mice both with and without iNOS induction, but microvascular leakage in septic mice was not increased in the absence of iNOS.
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In all B02 inoculated mice both tibias presented with bone tumour lesions.
31 Bmal1−/− mice (both genders) were treated with rapatar and 73 Bmal1−/− mice (both genders) treated with control solution were used for the longevity experiment.
and Who's Got Game?: The Lion or the Mouse?, both written with her son and published in 2003.
Other mice - both healthy ones and those with Alzheimer's symptoms - were given a dummy (placebo) treatment.
Four groups of mice, both control and tg mice with VMT (trained) and without VMT (naïve), were examined.
From Myf5nlacZ/+ mice, both populations formed myogenic colonies with numerous β-gal+ myonuclei and myoblasts.
We assessed whether mice with both reconstituted immunity and inoculation with Caski tumor cells possessed memory T cells with specific activity against cervical tumor cells in vitro.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com