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Additionally, high levels of IL-17A and IL-17F were detected as part of the aggravated immunophenotype of CCR9−/− mice both at the mRNA level and the protein level.
CD44 expression in RAL- and HAFi-treated SKH1 hairless or DBA/1 mouse back skin was more significantly increased than in RAL alone- or HAFi alone- treated skin of these mice both at the RNA and protein levels (Figure 3C, D).
This was examined using fluorescent probes and an isolated fiber preparation to examine NO content and superoxide in the cytosol and mitochondria of muscle fibers from adult and old mice both at rest and following contractile activity.
In the search for differentially regulated inflammatory genes in the diabetic retina, we discovered that IL-1β was predominant in retinal tissues of Ins2Akita-KO mice both at the transcript and protein levels.
The aim of this study was therefore to examine NO in muscle fibers from adult and old mice both at rest and following contractile activity and to determine the effect of any age-related changes in NO on the levels of superoxide detected in cytosol and mitochondria.
Histological analysis of Sgca null:Mlc1f-Nfix2 mice revealed a markedly worsened phenotype with respect to Sgca null mice, both at 5 (Fig. 5a) and 8 weeks (Fig. 5b).
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Hypotension and renal histological abnormalities in triple knockouts were comparable to those in mice lacking both AT(1) subtypes.
Myd88−/− mice were nonetheless normoglycemic both at rest and after an intra-peritoneal glucose tolerance test (IPGTT).
As suggested from early studies on the IKKβ and p65 knockout mice, both mice die at an early embryonic stage, due to hepatocyte cytotoxicity [26], [27], [101].
Myeloid leukemia has been extremely rare in both ATM deficient mice and AT patients (Onoda et al., 2013).
The epithelial compartment was then visualised with Cy3 (Invitrogen, anti-rabbit; anti-mouse, both used at 1∶25).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com