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Cdc42 cardiomyocyte knockout mice were generated by crossing Cdc42/flox mice with MLC-2a Cre mice, as previously reported [22].
Islets were isolated from 10- to 16-week-old mice as previously described (Rorsman and Trube 1986).
T cells were isolated from the spleens of female NMRI mice as previously described (Baumer et al. 2010).
Intraperitoneal injection of 1 mg of mtDAMPs was used as experimental model in wild type and RAGE KO mice, as previously described [1].
We generated patDp/+ mice as previously described [13].
BMDM were isolated from C57Bl6 mice, as previously described [46].
Murine bone marrow-derived dendritic cells (BMDCs) were generated from mice as previously described [38].
IGF-IR−/+ mice as previously described [19] were in pure C57BL/6 background.
Mouse dermal fibroblasts (DF) were derived from newborn mice as previously described [42].
AB was induced in C57BL/6 and CXCR5−/− mice as previously described [53].
Type II cells were isolated from 6 week old female mice as previously described [22].
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