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To investigate the functions of Tmub1 in vivo, we performed Tmub1 gene deletion in mice, as part of a collaborative effort between Genentech and Lexicon Pharmaceuticals to analyze the function of about 500 secreted and transmembrane proteins.
All work performed using mice as part of this study was approved by the appropriate Monash University Animal Ethics Committee and as such, all animal work followed the committee's guidelines and procedures.
However, Th2 CD4+ T cells and ILC2 cells are decreased in obese mice as part of the adipose tissue proinflammatory activation pathway.
We previously described hydrocephalus with craniofacial abnormalities in Stk36 (serine threonine kinase 36) KO mice as part of an analysis of 12 KO lines having hydrocephalus.
We have previously demonstrated that adiponectin production is down-regulated in WAT of mice as part of the inflammatory response to Lipopolysaccharide [ 21].
Neurotropism of the H5N1 virus in mice as part of the pathogenesis subsequent to infection by human influenza virus isolates has been reported (10).
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To test these possibilities, we combined our published CGG KI results with the data generated by other labs wherein they used the battery described above in Figure 1 to evaluate the cognitive deficits in the Fmr1 KO mouse as part of interventional treatment studies.
The skin and lung tissues from SENCAR mice used as part of the Environmental Protection Agency's (EPA's) Carcinogenesis Testing Matrix were examined.
> Murine kidney tissue was scavenged from mice sacrificed as part of experiments with full ethics approval and in accordance with the policies of the University of Adelaide Ethics Committee.
In the current article, we report the novel mis-sense mutation Y64H in amelogenin as underlying the AI phenotype observed in mice obtained as part of a large-scale ENU mutagenesis programme (http://www.gsc.riken.jp/Mouse/).jp/Mouse/
Dr. Lichtman and his team of researchers at Harvard have built some unusual contraptions that carve off slivers of mouse brains as part of a quest to understand how the mind works.
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