Sentence examples for mice as models from inspiring English sources

Focusing on simian virus 40 (SV40) and mechanisms of malignant transformation in cells, Jaenisch moved toward using mice as models for cancer research and became interested in the increased susceptibility to cancer exhibited by certain cell types.

This chapter discusses the potential of laboratory animals, and especially mice, as models of diseases and various pathophysiologic processes.

Investigators have sought to understand the pathogenesis of hematopoietic neoplasms in mice as models for human disease.

Transgenic fish are an interesting and valuable alternative to the use of transgenic mice as models for genome manipulation.

Moreover, the controlled disassembly of the hydrogel was monitored in real time by in vivo fluorescence imaging after subcutaneous injection using mice as models.

Essentially, this one study showed that we wasted decades of research using mice as models for human inflammatory diseases because no one thought until recently to actually take a look at how relevant the animal experiments are.

The success in producing the first transgenic mouse line that expressed rabbit β-globin protein in mouse erythrocytes three decades ago marked the beginning of the use of genetically engineered mice as model system to study human diseases.

While supporting a role for RNF5 Tg mice as model for s-IBM, our study also establishes the importance of RNF5 in muscle physiology and its deregulation in ER stress associated muscular disorders.

As demonstrated in other studies that employ mice as model organisms, the extrapolation of mouse data to humans must be approached with caution.

We report here our investigations on the role of p53 in the increased resistance to oxidative stress of longevous mice, using p66−/− mice as model.

We focused our attention on non−sensory cell networks of the developing cochlea and used organotypic cultures from P5 mice as model system.