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Glucose and insulin levels in the blood collected from the facial vein of the mice are shown.

The typical footprint patterns of control KO, treated KO and WT mice are shown in Fig. S2B.

(C) Fold changes in gene expression of 26 week old mice normalized to 10 week old mice are shown.

The results for locomotor activity over 60 min for risperidone-challenged mice are shown in Figure 1g.

The representative images of IgWAT, EpiWAT and BAT isolated from the differently treated mice are shown in (c).

Representative images of skin samples collected from both untreated and treated BCC mice are shown (n = 3 per treatment and time point).

Images of tumor samples from sacrificed mice are shown.

The time-activity and time-uptake curves for the six mice are shown in Fig. 3.

a Transversal and coronal micro-PET images of the mice are shown at different timepoint post-injection of tracer.

(A) Representative sequencing chromatographs of the PCR amplicons of target sites from the founder mice are shown here.

(A) The ratio of malignancy, pathological type, and metastasis in ATM−/− and ATM−/− Gadd45a−/− mice are shown.

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