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Immunocompetent mice are required to examine the full effect of the NS1 mutation on viral replication through IFN production and signaling.
All previous NASA missions in which mice were co-housed, involved female mice; however, in our spaceflight studies examining bone healing, male mice are required for optimal experimentation.
These mice are required for these investigations to determine several factors that contribute to the susceptibility for candidal infections.
In the context-dependent NOR task, mice are required to remember which objects are associated with a specific context (i.e., round vs. square arena).
Detailed analyses of the tissue T3 levels in the hypertrophic LV of control and transgenic mice are required to show that this is indeed the case.
i. Expected survival is 75% (as seen in Supplemental figure 10), thus 14 mice are required to predict 10 will survive.
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To prove the efficacy and safety of CAR-T cell therapy, the elucidation of immunological mechanisms underlying it in mice is required.
However, the increased expression of Krt16 after tibia fracture was not seen in neuropeptide-deficient mice.Collectively, these data support the hypothesis that neuropeptide signaling in the fracture limb of mice is required for autoantigenic IgM production and nociceptive sensitization.
Twenty-four mice were required for the study.
In some cases, the mice were required to remember that turning right always led to a reward, indicating that they had acquired the repetitive habit of turning right and their skill had become "unconscious".
In this task, mice were required to locate the hidden platform using distal extra-maze cues.
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