Sentence examples for mice are relevant from inspiring English sources

Here we try to analyze critically some of the information provided by transgenic mice but ascertaining which elements of the neuropathological and behavioural phenotype of these various strains of transgenic mice are relevant to that observed in Alzheimer′s disease continues to be a challenge.

The results of the present immunofluorescence studies on renal biopsies from SLE patients suggest that changes in Dnase1 expression similar to those seen in the B/W mice are relevant to explain disease progression also in humans.

Also, you need to defend the dosages of medicines that were given to mice and discuss whether the high doses in mice are relevant to humans.

Such a dual-species approach has the benefit of ensuring that the transcriptional correlates of disease severity identified in mice are relevant in human.

Whether the cardioprotective effects of remifentanil that were demonstrated in mice are relevant for cardiac surgery remains to be determined by further studies.

In this review, we present evidence that these studies in mice are relevant to normal human stem cell aging and we explore different hypotheses to explain the tissue-specific consequences of mtDNA mutations.

In order to study whether the increased fear response following 36-trials of footshock in tg mice was relevant to an anxiety-like behavioral phenotype, three groups of tg mice were subjected to naïve, 1 or 36 trials of footshock, respectively, and 24 hours later, these mice, together with control-naïve mice, were examined by using an open-field test.

Death of mTERC−/− mice was relevant to severe endotoxin shock and subsequent systemic inflammatory reaction as their serum circulating levels of IL6 and TNF-α reached greater than 4-fold within 2 h of LPS injection and 1.5 h before the first death (Fig. 2C).

Greater knowledge of the genetic and biochemical mechanisms underlying the germ-line modulation of lung tumor size in mice is relevant to other species, including humans, in that it may help identify new therapeutic targets in the fight against tumor progression.

Rodents and especially the house mouse are relevant to confront both aspects since their extensive phenotypic variation is documented in the wild (e.g. [ 1- 3]) and also because the house mouse is one of the most common laboratory models, providing an extensive background on genetic, developmental and environmental effects on various aspects of its phenotype.

To test whether changes in desmosomal components observed in mouse were relevant to the human condition, their expression was measured in primary keratinocytes derived from two AEC patients and healthy controls.