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Hence recordings in acute slices from APP overexpressing mice are obtained when extracellular Aβ is at a steady-state concentration, which is far lower than the concentration of Aβ in vivo.
Heterozygous mice, homozygous and wild-type mice are obtained by breeding from the same litter.
Genes that were significantly upregulated in E. histolytica HM-1 IMSS HM-1 IMSStrophozoiteshrough mice are obtained from Gilchrist et al [27] and are indicated by £.
We have included a statement reflecting the potential of shorting the study time to ensure enough mice are obtained for analysis.
As very low numbers of P-gp−/−::SOD1-G93A mice are obtained from these crosses, we limited our analysis to 5 6 mice per group to allow initial evaluation of the impact of P-gp knock down on disease and riluzole penetration.
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OT-II transgenic mice were obtained from the Jackson Laboratory.
Homozygous mutant mice were obtained by intercrossing the heterozygous littermates.
Male wild-type (WT) C57BL/6 mice were obtained (Jackson Laboratories).
BALB/c mice were obtained from the Laboratory Animal Unit of University of Hong Kong.
Compound mice were obtained by intercrossing heterozygotes.
Nore1−/− mice were obtained from Dr. Sean Lee.
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