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SerpinB1a-deficient mice are morphologically largely normal but were shown to have increased susceptibility to pulmonary infection by Pseudomonas aeruginosa [30].

The proerythroblastic cell lines derived from the spleen of diseased spi-1 transgenic mice are morphologically [9] and cytologically (our unpublished data) similar, and resemble CFU-E/proerythroblastic cells.

Heterozygous Prtg +/− mice are morphologically normal and fertile.

In contrast, Girk2 knock-out mice are morphologically indistinguishable from wild-type mice, suggesting that the weaver phenotype is likely due to abnormal Girk2 function [ 44].

However, as lipofuscin and the autofluorescent aggregates we observe in CHMP2BIntron5 mice are morphologically distinct, it is not clear whether a common upstream pathogenic pathway is shared or whether distinct neurodegenerative pathways converge on the lysosome.

Intriguingly, although the axonal swellings of SpastΔE7/ΔE7 mice are morphologically similar to those observed in the spinal cord of our Sp Δ/Δ mice, SpastΔE7/ΔE7 axonal swellings are stochastically distributed along the axons of cultured neurons (Kasher et al., 2009), whereas axonal swellings only occur in the distal part of Sp Δ/Δ axons in our cultures (Tarrade et al., 2006).

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Degenerating synapses in old wild-type mice were morphologically indistinguishable from those previously observed in young mice (c.f. Figure 2 with Figure 5).

After the ibuprofen treatment, the DCX+ cells in AICD transgenic mice were morphologically indistinguishable from those in wild-type mice (Fig. 5E).

Neutrophils harvested from the thioglycollate stimulated peritoneal cavity of BBEE and bbEE mice were morphologically mature with segmented nuclei (Figure 2).

Moreover, neutrophils isolated from the peritoneal space of TGA-treated STAT5−/− mice were morphologically mature and stained normally for Gr-1 and CD11b, two late-stage markers of neutrophil differentiation (data not shown).

The adipose tissues of VGFC57 and VGFR mutant mice were morphologically different from wild type mice.

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